Dopamine Agonist Withdrawal Syndrome in Parkinson Disease
نویسندگان
چکیده
منابع مشابه
Dopamine agonist withdrawal syndrome in Parkinson's disease.
OBJECTIVES To report and characterize a dopamine agonist (DA) withdrawal syndrome (DAWS) in Parkinson disease. DESIGN Retrospective cohort study. SETTING Outpatient tertiary movement disorders clinic. Patients A cohort of 93 nondemented patients with Parkinson disease enrolled in a prospective study of nonmotor and motor disease manifestations. Main Outcome Measure The presence of DAWS, def...
متن کاملCauses and factors related to dopamine agonist withdrawal in Parkinson′s disease
BACKGROUND Although dopamine agonists (DAs) are useful in Parkinson's disease (PD), they are not frequently used in elderly patients due to adverse effects. However, there is a lack of evidence because few elderly PD patients are enrolled in clinical trials. AIMS OF THE STUDY The aims of this study were to analyze the reasons of DA withdrawal (DAW) in a group of PD patients in clinical practi...
متن کاملUnderlying Mechanisms of Impulse Control Disorders and Dopamine Agonist Withdrawal Syndrome in Parkinson’s Disease
Recently, much attention has been paid to not only motor symptoms but also Non-Motor Symptoms (NMS) of Parkinson’s disease [1]. NMS include sleep disorders, autonomic nervous system dysfunction, sensory impairment, and neuropsychiatric symptoms. Neuropsychiatric symptoms include depression, apathy, anxiety, anhedonia, attention deficit, hallucinations, confusion, Impulse Control Disorders (ICD)...
متن کاملDopamine agonist withdrawal syndrome and non-motor symptoms after Parkinson's disease surgery.
We would like to thank Dr Nirenberg for her thoughtful comments on our prospective study reporting the occurrence of a delayed withdrawal syndrome in patients with Parkinson’s disease treated with bilateral subthalamic stimulation. This syndrome, which includes depression, apathy and anxiety, is the consequence of a marked decrease in dopaminergic treatment rendered possible by a major improvem...
متن کاملLETTER TO THE EDITOR Dopamine agonist withdrawal syndrome and non-motor symptoms after Parkinson’s disease surgery
Sir, I read with interest the manuscript by Dr Thobois and colleagues (Thobois et al., 2010), in which the authors report the occurrence of depression and apathy after deep brain stimulation surgery for Parkinson’s disease and correlate these symptoms with mesolimbic dopaminergic denervation on neuroimaging studies. I agree with the authors’ interpretation of post-surgical apathy as a drug with...
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ژورنال
عنوان ژورنال: Archives of Neurology
سال: 2010
ISSN: 0003-9942
DOI: 10.1001/archneurol.2009.294